The aim of this work was to evaluate the current situation of body mass index (BMI) values within the global population in terms of geographical region, cultural and economic differences. It was used to test the hypothesis that BMI values differ according to geographical region, culture, and economic performance. Based on statistical evaluation of data from 2010 and 2014 provided by the World Health Organisation (WHO), there has been a statistically insignificant increase in BMI in specific areas of the world. In both periods in question, North America led with the highest BMI values, whereas countries in the sub-Saharan Africa had the lowest BMI values. There were significant differences (p < 0.05) in the values of BMI between most evaluated areas. Similarly, there was a significant difference (p < 0.05) between economically developed and economically less developed countries. However, the increase in BMI values between 2010 and 2014 was statistically inconclusive in both economies.The highest BMI in the monitored period was detected in Christian countries, followed by Islamic countries, and finally in countries where Buddhism and Hinduism are the dominant religions. In this context, among economically less-developed countries, Christian countries had the highest BMI values, whereas among economically developed countries Islamic countries had the highest BMI values. There was no significant difference in BMI values between economically developed and economically less-developed Buddhist and Hinduism countries. Thus, the hypothesis was judged correct.