Nucleolus precursor bodies and ribosome biogenesis in early mammalian embryos: old theories and new discoveries

FULKA, Helena and AOKI, Fugaku. Nucleolus precursor bodies and ribosome biogenesis in early mammalian embryos: old theories and new discoveries. Biology of Reproduction, 2016, 94, 143, 1-8. ISSN 0006-3363.
Year2016
CathegoryScientific publication in impacted journals
Internal link16059.pdf
Abstract

In mammals, mature oocytes and early mammalian embryos contain transcriptionally inactive structures – nucleolus precursor bodies. These structures are essential only in a very short time interval post fertilization. They do not participate in embryo nucleologenesis and thus they are not involved in ribosome biogenesis.