The aim of the study was to calculate economic values (EV) for a complex of production, functional, slaughter traits and feed efficiency using a universal bio-economic model of the EWPIG program. The traits EV were calculated for breeds included in the 4-breed production system of the national program CzePig (Czech Large White, Czech Landrase, Pietrain and Duroc). EVs expressed the change in profit by increasing the trait level in the given breed by one unit, taking into account the structure of the hybridization program. In dam breeds, the order of the traits economic importance was as follows: health (41%), reproduction (21%), feed conversion (17%), carcass traits (9%) and number of functional teats (5%). For sire breeds, next to the health (35%), feed conversion (22%) and carcass traits (20%) also the sperm quality (13%) and growth (8%) were found as important traits. Similar to the 3-breed production system, the economic importance of the traits was confirmed in maternal breeds. The updated proportion of traits in the Pietrain breed corresponds to the change in the population structure of this breed and its importance in a four-breed hybridization program. Proportion of the traits in sire breeds is influenced by their position in a given hybrid combination of a boar produced to reach the final hybrids. EV traits calculated for other sire breeds would have very similar values compared to the evaluated sire breeds. The results also show that these traits should be taken into account in the breeding of the domestic pig population in the future.