The aim of this study was the evaluate the effect of lactation and weaning diets based on whole white lupin seeds on milk yield (two lactation period) of the rabbit does, as well as on reproductive performance and growth performance of their litters. It can be concluded that whole white lupin seeds is a suitable protein source for Iactating rabbit does, which can fully replace soybean and sunflower meal. The lactation diet based on whole white lupin led to higher milk yield and do not significantly reduce reproductive performance or growth performance of their litters.