Production of mouse embryonic stem cell lines from maturing oocytes by direct conversion of meiosis into mitosis

FULKOVÁ, H., HIROSE, M., INOUE, K., OGONUKI, N., WAKISAKA, N., MATOBA, S., OGURA, A., MOŠKO, T., KOTT, T. & FULKA, Jr., J. Production of mouse embryonic stem cell lines from maturing oocytes by direct conversion of meiosis into mitosis. Stem Cells, 2011,
FULKA, Helena, HIROSE, Michiko, INOUE, Kimiko, OGONUKI, Narumi, WAKISAKA, Noriko, MATOBA, Shogo, OGURA, Atsuo, MOŠKO, Tibor, KOTT, Tomáš and FULKA, Josef Jr. Production of mouse embryonic stem cell lines from maturing oocytes by direct conversion of meiosis into mitosis. Stem Cells, 2011, 29, 517-527. ISSN 1066-5099.
Year2011
CathegoryScientific publication in impacted journals
Internal link11021.pdf
Abstract

Described is a novel approach where ESC with all pluripotency parameters were established from oocytes in which metaphase I was converted directly into metaphase II-like stage. The embryos initiate development and reach the blastocyst stage from which the ESC lines are established.