RNA polymerase II transcriptional silencing in growing and fully grown germinal vesicle oocytes isolated from gonadotropin-stimulated and non-stimulated gilts

BARNETOVÁ, I., MOROVIC, M., STREJČEK, F., OSTRUP, O., HYTTEL, P., NEIMANN, H., LAURINČIK, J., FULKA, Jr., J. & FULKOVÁ, H. RNA polymerase II transcriptional silencing in growing and fully grown germinal vesicle oocytes isolated from gonadotropin-stimulate
BARNETOVÁ, Irena, MOROVIC, Martin, STREJČEK, František, OSTRUP, Olga, HYTTEL, Poul, NEIMANN, Heiner, LAURINČIK, Jozef, FULKA, Josef, Jr. and FULKA, Helena. RNA polymerase II transcriptional silencing in growing and fully grown germinal vesicle oocytes isolated from gonadotropin-stimulated and non-stimulated gilts. Molecular Reproduction and Development, 2012, 79, 697-708. ISSN 1040-452X.
Year2012
CathegoryScientific publication in impacted journals
Internal link12124.pdf
Abstract

Global transcriptional silencing occurs in the oocyte during its final phase of growth. The particular mechanisms of this silencing is not well understood. In our experiments we investigated the silencing of RNA polymerase II transcription in growing and fully grown porcine oocytes.