Somatic cell score: gene polymorphisms and other effects in Holstein and Simmental cows

ČÍTEK, Jindřich, BRZÁKOVÁ, Michaela, HANUSOVÁ, Lenka, HANUŠ, Oto, VEČEREK, Libor, SAMKOVÁ, Eva, JOZOVÁ, Eva, HOŠTIČKOVÁ, Irena, TRÁVNÍČEK, Jan, KLOJDA, Martin and HASOŇOVÁ, Lucie. Somatic cell score: gene polymorphisms and other effects in Holstein and Simmental cows. Animal Bioscience, 2022, 35, 13-21. ISSN 2765-0189.
Year2022
CathegoryScientific publication in impacted journals
Internal link22004.pdf
Abstract

Objective: The aim of the study was to evaluate the influence of gene polymorphisms and nongenetic factors on the somatic cell score (SCS) in the milk of Holstein (n = 148) and Simmental (n = 73) cows and their crosses (n = 6). Methods: The SCS was calculated by the formula SCS = log2(SCC/100,000)+3, where SCC is the somatic cell count. Polymorphisms in the casein alpha S1 (CSN1S1), beta-casein (CSN2), kappa-casein (CSN3), beta-lactoglobulin (LGB), acyl-CoA diacylglycerol transferase 1 (DGAT1), leptin (LEP), fatty acid synthase (FASN), stearoyl CoA desaturase 1 (SCD1), and 1-acylglycerol-3-phosphate O-acyltransferase 6 (AGPAT6) genes were genotyped, and association analysis to the SCS in the cow’s milk was performed. Further, the impact of breed, farm, year, month of the year, lactation stage and parity on the SCS were analysed. Phenotype correlations among SCS and milk constituents were computed by Pearson correlation coefficients. Results: Only CSN2 genotypes A(1)/A(2) were found to have significant association with the SCS (p