Absence of maternal cell contamination in mesenchymal stromal cell cultures derived from equine umbilical cord tissue

VACKOVÁ, Irena CZERNEKOVÁ, Vladimíra, TOMÁNEK, Milan, NAVRÁTIL, J., MOŠKO, Tibor a NOVÁKOVÁ, Zora. Absence of maternal cell contamination in mesenchymal stromal cell cultures derived from equine umbilical cord tissue. Placenta, 2014, 35, 655-657. ISSN 0143-4004.
Kateg. publikaceVědecké publikace impaktované
Interní odkaz14066.pdf
Abstrakt

This study aimed to determine whether maternal cell contamination exists in cells derived from equine umbilical cord tissue, a perspective material for cell-based therapies in veterinary medicine. Potential maternal cell contamination was analyzed at DNA level via a set of 16 microsatellite markers in cells originating from the cord tissue of 22 foals. In these cells no maternal cell contamination was detected at a sensitivity level of 0.01%. Our results suggest that equine umbilical cord tissue-derived cells are entirely of fetal origin.

ProjektUdržitelný rozvoj chovu hospodářských zvířat v evropském modelu multifunkčního zemědělství
OdděleníBiologie reprodukce, Genetika a šlechtění hospodářských zvířat