Assessment of the Genetic Diversity of a Local Pig Breed Using Pedigree and SNP Data
Kateg. publikace | Vědecké publikace impaktované |
Interní odkaz | 21214.pdf |
Abstrakt | Herein, the genetic diversity of the local Přeštice Black-Pied pig breed was assessed by the simultaneous analysis of the pedigree and single nucleotide polymorphism (SNP) data. The information about sire line, dam, date of birth, sex, breeding line, and herd for 1971 individuals was considered in the pedigree analysis. The SNP analysis (n = 181) was performed using the Illumina PorcineSNP60 BeadChip kit. The quality of pedigree and SNPs and the inbreeding coefficients (F) and effective population size (Ne) were evaluated. The correlations between inbreeding based on the runs of homozygosity (FROH) and pedigree (FPED) were also calculated. The average FPED for all animals was 3.44%, while the FROH varied from 10.81% for a minimum size of 1 Mbp to 3.98% for a minimum size of 16 Mbp. The average minor allele frequency was 0.28 ± 0.11. The observed and expected within breed heterozygosities were 0.38 ± 0.13 and 0.37 ± 0.12, respectively. The Ne, obtained using both the data sources, reached values around 50 animals. Moderate correlation coefficients (0.49–0.54) were observed between FPED and FROH. It is necessary to make decisions that stabilize the inbreeding rate in the long-term using optimal contribution selection based on the available SNP data. |
Projekt | Dlouhodobý koncepční rozvoj výzkumné organizace, Vytvoření referenční populace a vývoj postupů pro odhad genomických plemenných hodnot znaků prasat zařazených do Českého národního šlechtitelského programu |
Oddělení | Genetika a šlechtění hospodářských zvířat |
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