The presented microclimate control model to provide animal welfare and immunity uses a combination of natural and forced ventilation and a sorbent to remove ammonia from the air in the pig farm buildings. The model is based on the next controlled processes: the three-level system of windows and vents for ventilation of air: at the floor level, at the level of the pig growth and at a height of 1-1.5 m above their growth;air purification from ammonia to ensure its safe content of 0.0025% vol.;air cooling or heating to maintain an optimal temperature 15-200C;spray-ing water (irrigation) to regulate the optimal air humidity 50-70%.Microclimate control parameters are measured using sensors at three levels inside the building: indoor temperature and humidity, humidity above the floor and floor bedding, ammonia and carbon dioxide concentration, air velocity (air inflow velocity), outdoor temperature and humidity. Pig condition control parameters for thermoregulation are the temperature of individual body parts and skin moisture; for welfare – pig immunity and hormone biomarkers. The control parameters are automatically regulated according to the algorithm and adapted software at deviations of 15-20%. A sorbent based on natural hu-mic substances with a humic acid content of min 62% was developed to clean the air from ammonia. This sorbent can be used in adsorbers and as component of a floor bedding. Thermal activation was carried out at a temperature of 60 to 1050C. This method is a simple, inexpensive and industrially scalable. The processes of sorption – de-sorption of ammonia and water at 180C were studied. The amount of adsorbed ammonia and water was 5-10 times greater for thermoactivated samples than for undried ones. Ammonia sorption under static conditions above 2% aqueous ammonia solutions was 0.8% for activated samples after 1 h, after 4 h – 2.2%, after 24 h – 7.5%, after 10 days – 24.3%. Sorption of water vapor was 4.7% after 24 h, 13.8% after 10 days. The intensive evaporation of ammonia was 22.1% from activated samples for the first hour of desorption. This activated sorbent can be added to the floor bedding for air purification in farms.