Do cloned mammals skip a reprogramming step?

FULKA, Josef Jr., MIYASHITA, N., NAGAI, T. a OGURA, A. Do cloned mammals skip a reprogramming step?. Nature Biotechnology, 2004, 22, 25-26. ISSN 1087-0156.
Kateg. publikaceVědecké publikace impaktované
Interní odkaz4203.pdf

Cloned animals are widely accepted to have an attenuated lifespan compared with their conventionally bred counterparts. Here we argue that these problems arise because the process of nuclear transfer used to create cloned animals skip one of the two essential, independent steps involved in the reprogramming of cell nuclei.

OdděleníBiologie reprodukce
Pracovní skupinaEmbryobiotechnologie