In total 593 goats were genotyped on 5 single nucleotide polymorphisms (SNP): one SNP at Lactoferrin in exon 4 and four SNPs at Toll-like receptor 4 in exon 3 by using SNaPshot minisequencing. The most prevalent genotype was TT (546) in LF and genotype combination TTCCCCGC (216) and TTCCCCCC (204) in TLR4. There is possible influence of LF and TLR4 on milk yield and milk components, therefore, further studies are needed to evaluate this possible association in more number of goat farms.