Production of mouse embryonic stem cell lines from maturing oocytes by direct conversion of meiosis into mitosis

FULKOVÁ, Helena, HIROSE, Michiko, INOUE, Kimiko, OGONUKI, Narumi, WAKISAKA, Noriko, MATOBA, Shogo, OGURA, Atsuo, MOŠKO, Tibor, KOTT, Tomáš a FULKA, Josef Jr. Production of mouse embryonic stem cell lines from maturing oocytes by direct conversion of meiosis into mitosis. Stem Cells, 2011, 29, 517-527. ISSN 1066-5099.
Kateg. publikaceVědecké publikace impaktované
Interní odkaz11021.pdf
Abstrakt

Described is a novel approach where ESC with all pluripotency parameters were established from oocytes in which metaphase I was converted directly into metaphase II-like stage. The embryos initiate development and reach the blastocyst stage from which the ESC lines are established.

ProjektUdržitelný rozvoj chovu hospodářských zvířat v evropském modelu multifunkčního zemědělství
OdděleníBiologie reprodukce, Genetika a šlechtění hospodářských zvířat
Pracovní skupinaEmbryobiotechnologie