The effect of caprylic acid against salmonellas was investigated in broiler chickens. Caprylic acid added to the feed of broiler chickens at 2.5 g/kg, experimentally contaminated with Salmonella Enteritidis, significantly decreased counts of salmonellas in crop and caecum. The effect of caprylic acid in the crop contents was more pronounced than in the caecum. It can be concluded that caprylic acid is able to reduce numbers of salmonellas in the gastrointestinal tract of chickens and has a potential to improve health status of infected animals.