Genomic breeding values (GEBV) for clinical mastitis (CM) and three groups of foot and claw disorders (CD): infectious digital disorders (IDD), claw horn lesions (CHL) and overall claw disorders (OCD) were predicted for Holstein cows in the Czech Republic. Subsequently, a health index was calculated using predicted GEBVs. The official web application Diary of Diseases and Medication was a source of health records. Datasets included: CM data from 178,107 lactations of 100,873 Holstein cows on 126 farms; IDD 89,727; 50,244; 54; CHL 59,350; 32,687; 35; OCD 121,585; 67,729; 73, respectively, from 2017 to 2022. The linear animal model and single-step genomic prediction were employed for each health trait separately using the Program package BLUPF90 (Misztal et al. 2018).