Increasing productivity, improving milk composition, and boosting milk yield are of great economic impor­tance for the dairy industry. Goat milk is appealing for its nutritional aspects, healthy properties, and func­tional food effects. Milk traits can be modified exten­sively by both environmental and genetic factors. The aim of this study was to investigate variation at the BTN1A1, SCD, and LPL loci and to investigate the ef­fects of genetic variants of BTN1A1 (exon 4), SCD (exon 3 and intron 3), and LPL (signal peptide and intron 1) genes on goat milk traits in White Shorthaired goats kept in the Czech Republic.