The purpose of this study was to evaluate the effect of substituting soybean meal (SBM) for whole white lupin seeds (WL) or sunflower meal (SFM) as protein source for growing-fattening rabbits. Weaned Hyplus rabbits were individually housed and fed one of the three experimental diets. At the end of the trial period, the slaughtered rabbits were used for the evaluation of carcass traits. The coefficient of total tract apparent digestibility (CTTAD) of the diets and caecal traits were determined. Feed intake was significantly higher with the SFM diet. Dressing-out percentage was higher in rabbits fed the WL diet than in rabbits fed the other diets. Diet did not affect CTTAD. Rabbits fed the SFM diet had significantly lower neutral detergent fibre digestibility. Lactic acid concentration was significantly increased with WL feeding. It is concluded that whole white lupin seeds can replace satisfactorily soybean meal and sunflower meal in diets for growing-fattening rabbits.