Analysis of chromatin structure in mouse preimplantation embryos by fluorescent recovery after photobleaching
| Year | 2016 |
| Cathegory | Scientific publication in impacted journals |
| Internal link | 16027.pdf |
| Abstract | Zygotes are totipotent cells that have the ability to differentiate into all cell types. It is believed that this ability is lost gradually and differentiation occurs along with the progression of preimplantation development. We show that the loose chromatin structure is involved in the totipotency of one-cell stage embryos and that the change from loose to tight chromatin structure is associated with the loss of totipotency. |
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