De novo formation of nucleoli in developing mouse embryos originating from enucleolated oocytes

KYOGOKU, H., FULKA, Jr., J., WAKAYAMA, T. & MI, T.YANO De novo formation of nucleoli in developing mouse embryos originating from enucleolated oocytes. Development, 2014, roč. 141, s. 2255-2259. {INTLINK}
KYOGOKU, H., FULKA, Josef Jr., WAKAYAMA, T. and MI, T.YANO De novo formation of nucleoli in developing mouse embryos originating from enucleolated oocytes. Development, 2014, 141, 2255-2259. ISSN 0950-1991.
Year2014
CathegoryScientific publication in impacted journals
Internal link14047.pdf
Abstract

It is commonly accepted that nucleoli in one-cell stage embryos are gradually transformed into differentiated tripartite nucleoli. In our article, we break this dogma as we show, that when nucleoli are removed from late one-cell stage embryos, these embryos develop with a de novo formation of nucleoli.